James N Ingle Selected Research

Cytochrome P-450 CYP2D6 Inhibitors

1/2018	Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
11/2011	Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials.

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James N Ingle Research Topics

Disease

182	Breast Neoplasms (Breast Cancer) 06/2022 - 01/2002
92	Neoplasms (Cancer) 06/2022 - 02/2002
15	Triple Negative Breast Neoplasms 06/2022 - 01/2013
11	Neoplasm Metastasis (Metastasis) 05/2021 - 06/2002
7	Disease Progression 04/2018 - 09/2003
7	Osteoporosis 07/2017 - 11/2003
5	Pain (Aches) 01/2018 - 11/2003
4	Bone Fractures (Bone Fracture) 07/2016 - 09/2005
4	Noninfiltrating Intraductal Carcinoma (DCIS) 11/2015 - 06/2002
4	Melanoma (Melanoma, Malignant) 06/2007 - 01/2006
3	Arthralgia (Joint Pain) 01/2018 - 11/2003
3	T-Cell Leukemia (Leukemia, T Cell) 01/2018 - 03/2012
2	Pathologic Complete Response 01/2018 - 01/2017
2	Endometrial Neoplasms (Endometrial Cancer) 10/2017 - 08/2013
2	Metabolic Bone Diseases (Osteopenia) 07/2017 - 04/2013
2	Drug-Related Side Effects and Adverse Reactions 01/2017 - 03/2012
2	Inflammation (Inflammations) 01/2017 - 01/2010
2	Musculoskeletal Pain 03/2016 - 03/2012
2	Bone Resorption 01/2014 - 08/2006
2	Uterine Hemorrhage (Uterine Bleeding) 04/2013 - 11/2003
2	Colorectal Neoplasms (Colorectal Cancer) 01/2013 - 02/2006

Drug/Important Bio-Agent (IBA)

65	Tamoxifen FDA LinkGeneric 01/2021 - 01/2002
44	Aromatase InhibitorsIBA 02/2022 - 08/2002
39	Estrogen ReceptorsIBA 01/2020 - 11/2002
36	Hormones (Hormone)IBA 02/2022 - 08/2002
26	Estrogens (Estrogen)FDA Link 01/2022 - 01/2002
25	Letrozole (Femara)FDA LinkGeneric 02/2022 - 09/2003
24	Anastrozole (Arimidex)FDA LinkGeneric 01/2022 - 08/2002
22	exemestane (Aromasin)FDA Link 01/2022 - 09/2003
15	Pharmaceutical PreparationsIBA 06/2022 - 07/2006
14	Biomarkers (Surrogate Marker)IBA 01/2021 - 06/2007
14	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2018 - 12/2005
14	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2015 - 02/2003
13	4-hydroxy-N-desmethyltamoxifenIBA 01/2021 - 12/2005
13	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2015 - 03/2003
12	Trastuzumab (Herceptin)FDA Link 01/2021 - 06/2002
12	Paclitaxel (Taxol)FDA LinkGeneric 09/2015 - 02/2003
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2002
11	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 10/2009
10	Progesterone Receptors (Progesterone Receptor)IBA 01/2020 - 11/2002
9	Selective Estrogen Receptor Modulators (SERM)IBA 10/2017 - 08/2007
8	Aromatase (CYP19)IBA 01/2020 - 11/2004
8	Estrogen Receptor alphaIBA 01/2018 - 08/2007
7	AnthracyclinesIBA 01/2021 - 07/2004
7	ErbB Receptors (EGF Receptor)IBA 12/2011 - 09/2004
6	Phenobarbital (Luminal)FDA Link 06/2022 - 09/2014
6	Diphosphonates (Bisphosphonates)IBA 05/2021 - 02/2002
6	Estradiol (Delestrogen)FDA LinkGeneric 01/2020 - 08/2009
6	CytokinesIBA 01/2018 - 06/2002
6	EnzymesIBA 11/2011 - 01/2007
5	Fulvestrant (Faslodex)FDA Link 01/2021 - 03/2006
5	ParaffinIBA 12/2014 - 12/2005
4	RNA (Ribonucleic Acid)IBA 10/2021 - 07/2004
4	Aurora Kinase AIBA 01/2021 - 10/2017
4	taxaneIBA 01/2021 - 07/2004
4	P-2 (P 2)IBA 10/2017 - 07/2013
4	Raloxifene Hydrochloride (Evista)FDA Link 01/2015 - 06/2011
4	Transforming Growth Factor beta (TGF-beta)IBA 07/2011 - 06/2002
4	VaccinesIBA 08/2010 - 08/2006
3	Androgen Receptors (Androgen Receptor)IBA 06/2022 - 10/2013
3	Estrogen Receptor betaIBA 02/2022 - 03/2011
3	HLA-DR Antigens (HLA-DR)IBA 10/2021 - 01/2010
3	Zoledronic Acid (Zometa)FDA Link 05/2021 - 07/2010
3	Docetaxel (Taxotere)FDA Link 01/2021 - 01/2005
3	AntibodiesIBA 01/2020 - 08/2011
3	Estrone FDA Link 01/2020 - 01/2010
3	afimoxifene (hydroxytamoxifen)IBA 06/2019 - 03/2009
3	human ERBB2 proteinIBA 11/2017 - 01/2010
3	Formaldehyde (Formol)FDA Link 12/2014 - 08/2011
3	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2013 - 12/2005
3	DNA AdductsIBA 10/2012 - 05/2008
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2012 - 06/2002
3	Estrogen Receptor Modulators (Antiestrogen)IBA 03/2009 - 11/2004
3	Messenger RNA (mRNA)IBA 08/2006 - 06/2002
3	Carboplatin (JM8)FDA LinkGeneric 01/2006 - 01/2005
2	Clodronic Acid (Clodronate)IBA 05/2021 - 01/2020
2	Ibandronic Acid (Boniva)FDA Link 05/2021 - 01/2020
2	LigandsIBA 01/2020 - 06/2002
2	Long Noncoding RNAIBA 01/2019 - 12/2016
2	olaparibIBA 12/2018 - 01/2017
2	MLN 8237IBA 04/2018 - 10/2017
2	Cytochrome P-450 CYP2D6 InhibitorsIBA 01/2018 - 11/2011
2	Bevacizumab (Avastin)FDA Link 01/2018 - 01/2018
2	ClaudinsIBA 01/2018 - 07/2011
2	Biological ProductsIBA 12/2017 - 02/2012
2	Cell-Free Nucleic AcidsIBA 10/2017 - 03/2017
2	Steroid Receptors (Steroid Receptor)IBA 01/2017 - 12/2006
2	Tumor Biomarkers (Tumor Markers)IBA 01/2016 - 05/2005
2	OsteoprotegerinIBA 10/2014 - 06/2002
2	Cyclin EIBA 09/2014 - 12/2006
2	Phosphotransferases (Kinase)IBA 09/2014 - 01/2014

Therapy/Procedure

87	Therapeutics 06/2022 - 01/2002
29	Drug Therapy (Chemotherapy) 01/2022 - 02/2003
14	Adjuvant Chemotherapy 02/2021 - 03/2003
10	Neoadjuvant Therapy 06/2022 - 01/2010
3	Chemoprevention 01/2020 - 11/2011
3	Aftercare (After-Treatment) 12/2006 - 01/2005
2	Radiotherapy 02/2021 - 01/2020
2	Precision Medicine 12/2018 - 06/2013
2	Segmental Mastectomy (Lumpectomy) 11/2015 - 05/2007